[Bioperl-l] Fwd: Announcing Ngila 1.2.1 Alignment Program
Hilmar Lapp
hlapp at duke.edu
Tue Aug 28 22:13:32 UTC 2007
Is anyone thinking about adding support for this as an aligner
option? I'm not sure whether aside from a Bio::Tools::Run module we'd
also need a format parser - it sounds like it's emitting clustalw
format?
-hilmar
Begin forwarded message:
> From: evoldir at evol.biology.mcmaster.ca
> Date: August 28, 2007 3:02:19 AM EDT
> Subject: Other: Announcing Ngila 1.2.1 Alignment Program
> Reply-To: racartwr at ncsu.edu
>
>
> Ngila is a global, pairwise alignment program that uses logarithmic
> and
> affine gap costs, i.e. C(g) = a+b*g+c*ln(g). These gap costs are more
> biologically realistic than the more popular (and efficient) affine
> gap
> cost model.
>
> I have recently completed updating the program to version 1.2.1. The
> new version includes two new, evolutionary alignment models based
> on my
> current research. These models allow you to find the maximum
> alignment
> of two sequences based on biological, evolutionary parameters---no
> more
> guessing at biological costs. Additional changes are noted on the
> website.
>
> Website & Manual:
>
> http://scit.us/projects/ngila/
>
> Windows Binary:
>
> http://scit.us/projects/files/ngila/Releases/ngila-release-win32.zip
>
> Unix/Mac Source Code:
>
> http://scit.us/projects/files/ngila/Releases/ngila-release.tar.gz
>
> I'll be happy to answer any questions users have about the new
> models or
> the program.
>
> --
> *********************************************************
> Reed A. Cartwright, PhD http://scit.us/
> Postdoctoral Researcher http://www.dererumnatura.us/
> Department of Genetics http://www.pandasthumb.org/
>
> Bioinformatics Research Center
> North Carolina State University
> Campus Box 7566
> Raleigh, NC 27695-7566
>
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