[Bioperl-l] Re: MicroarrayIO proposal
Allen Day
allenday@ucla.edu
Mon, 14 Oct 2002 17:00:26 -0700 (PDT)
> It *would* be cool to create MAGE-perl adaptor or wrapper classes that could
> live within Bioperl. This would enable bioperlers to make use of the
> MAGE-perl code for handling MAGE-ML data. I haven't thought much about
> specifics here, but would be interested if others have ideas along these
> lines.
>
> Allen's modules serve mostly to help parse various non-MAGE-ML file formats
> containing expression data, a worthy cause which is outside the scope of
> MAGEstk. All we'd really need to tie into the MAGE world would be some
> adaptors that could interconvert his objects with MAGE-perl objects.
I might like to work on this.
> For the record, here's how Affy array layout data is mapped to the
> feature/reporter MAGE system:
>
> Single spot (cell) on an array = Feature
> Perfect match cell + its mismatch cell = Reporter
> All probe pairs (PM+MM) in a probe set = CompositeSequence
According to the definition above:
Probeset.pm => CompositeSequence
Probe.pm => Feature
I haven't modeled the "Reporter" layer.
I'll have a look at the MAGE-perl classes and see if I can borrow some
method/class names.
-Allen