[EMBOSS] dicodon rankin software, Perl to C translation

Marvin Stodolsky marvin.stodolsky at gmail.com
Mon Mar 5 17:37:19 UTC 2012


It is well established that there are species specific biases in codon
and dicodon usage which strongly affect the efficiency of mRNAs
translation.  There are a few companies offering protein production
services, based on calculating these biases and "recoding" mRNAs for
better expression in new host species.

I have worked up dicodon calculation software, which I want to put in
the public domain.
The problem is that I have no formal IT training the code is a
heterogenous hack.
It draws on:
some EMBOSS binaries
PERL scripts donated by my son (an IT professional)
and some Linux binaries
all called through my hack of a master BASH script

It would clearly be best of all of the above could be combined into
some EMBOSS functionality.
Thus a collaborator(s) are being sought to wok this through.

I am 72 and retired, and do not at this time want to start a new
career learning C coding.
So anyone interested please contact me.
Through mid March I am traveling until returning to the Wash DC area.
So my responses may be slow until then.

Sincerely:

Marvin Stodolsky, Ph.D Biophysics
retired from the US Dept. of Energy, Office of Science, Office of
Biological & Environ.  Rsch



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