Hi Trina, Try re-installing. But this time install as 'su' (Super user) in this Unix shell. Regards Teja -- View this message in context: http://old.nabble.com/Installing-Bioperl-1.6.1-on-Mac-OS-10.6.7-tp31787371p31788966.html Sent from the Perl - Bioperl-L mailing list archive at Nabble.com.