Hi, This isnt really a bioperl query. But does anyone know how I can substitute all special characters (+ some other things) in a string with nothing in perl? I mean if I have a string like Cyclic-2,3-bisphospho-D-glycerate and I want ouput as bisphosphoglycerate. I want to remove -D-, Cyclic-, 2,3- etc. -- -Neeti Even my blood says, B positive