[Bioperl-l] About array CGH data based on BAC clones

Sean Davis sdavis2 at mail.nih.gov
Tue Oct 18 15:58:29 EDT 2005


On 10/18/05 3:03 PM, "Alex Zhang" <mayagao1999 at yahoo.com> wrote:

> Hello everyone,
> 
> Is there anybody who has the experience of
> analyzing array CGH data based on BAC clones
> to identify the BACs which are amplified or
> deleted(gain or loss)? Any soft tools or
> packages recommended?

You really probably want to be looking at the bioconductor project
(http://www.bioconductor.org).  Perl just isn't (currently) the right tool
for the job.  Bioconductor is probably the most advanced and flexible
framework for much of array analysis, including CGH.  Look at the aCGH,
DNAcopy, and GLAD packages, for starters.

Sean



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