[Bioperl-l] Bio::Prospect:: -- a Perl interface to Prospect protein
threading
Reece Hart
rkh at gene.com
Wed Feb 18 16:31:05 EST 2004
bioperl-l gang:
We're pleased to announce the first public release of Bio::Prospect::, a
Perl API for protein fold recognition with Prospect PRO. A
mini-manuscript describing the module is available at
http://prdownloads.sourceforge.net/prospect-if/manuscript.pdf?download.
Abstract
We present Bio::Prospect::, an object-oriented Perl Application
Programming Interface (API) to the PROSPECT protein threading
application. The Bio::Prospect:: modules facilitate executing
the program, parsing the results, generating a homology model
from an alignment, preparing a model for display with RasMol,
and reconciling multiple pairwise alignments as a single
multiple sequence alignment. The Bio::Prospect:: modules provide
for local and remote execution of PROSPECT via a consistent
interface. PROSPECT results may be represented with the
full-featured Thread class or as a space-efficient distillation
of results with the ThreadSummary class; instances of both
classes may be serialized for network transmission of results
from remote execution.
LICENSE: The module is released under the Academic Free License v. 2.0
(http://www.opensource.org/licenses/afl-2.0.php).
AVAILABILITY: The project is hosted on SourceForge
(http://www.sourceforge.net/projects/prospect-if/). A perl install
package is available through CPAN (http://search.cpan.org/~reece/).
Example scripts are included.
REQUIREMENTS: This module requires Prospect PRO
(http://www.bioinformaticssolutions.com/products/prospect.php) and
several other perl modules, all available from CPAN.
Comments, bug reports, patches, and code contributions are encouraged.
Happy Threading,
Reece Hart and David Cavanaugh
--
Reece Hart, Ph.D. rkh at gene.com, http://www.gene.com/
Genentech, Inc. 650/225-6133 (voice), -5389 (fax)
Bioinformatics and Protein Engineering
1 DNA Way, MS-93 http://www.in-machina.com/~reece/
South San Francisco, CA 94080-4990 reece at in-machina.com, GPG: 0x25EC91A0
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