[Bioperl-l] matching miRNAs to one or a lot of mRNAs

[Starr Hazard]

Folks,

In a recent paper, Kawasacki et al(pubmed 12808467) report on the 
interaction between a specific miRNA (human miRNA23 g.i. 17646028) and a 
specific mRNA (human HES1 g.i. 8400709). They suggest they did a BLAST 
search and ultimately located the interaction. I cannot duplicate their 
data mining and cannot find the association they describe.

In general, is there a way to take a library of miRNAs and evaluate their 
potential interaction with a particular mRNA? Or is there a data mining 
tool that could screen a large pool of mRNAs for
significant interactions with a pool miRNAs?

I cannot at present see any BioPerl tools that address this issue (right 
now that means I scanned the FAQ for the string RNA and searched the 
BioPerl site for RNA but found only some traffic about Seq.pm).The people I 
have asked seem divided about whether this is
text matching issue or more of a hybridization issue involving
an energy of interaction evaluation.

Anybody got any pointers to offer?

Starr