[Biojava-dev] WG: pI Calculation in BioJava

David Huen smh1008 at cam.ac.uk
Mon Apr 11 19:05:28 EDT 2005


I implemented the original version in Biojava but I don't know if it is 
still the same one being used. The original just used the pKa's of the 
amino acids and computed the pI by assuming that each AA ionised 
independently of the others. The pI was the pH at which the next charge was 
zero. The pKa's used were the same as those used in GCG.



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