[EMBOSS] how string is shuffleseq
Daniel Barker
db60 at st-andrews.ac.uk
Mon Aug 4 15:06:11 UTC 2008
Dear Derek,
Not a direct answer to your question - but there was an interesting
paper on shuffling recently, did you see it:
Jiang et al. (2008) uShuffle: A useful tool for shuffling biological
sequences while preserving the k-let counts. BMC Bioinformatics 9: 192.
Best wishes,
Daniel
Derek Gatherer wrote:
> Dear EMBOSS experts
>
> How good a shuffler is shuffleseq? I have always believed that it
> shuffles beyond all recognition, since tracer words inserted into a
> database are always gone after 1 round of shuffling. But are there any
> hard test data on its shuffling strength? For instance, for any, say,
> 100-mer, what fragments would reasonably be expected to remain after
> shuffling? Should I be surprised to see a 15-mer from the 100-mer still
> intact??
>
> Sorry I can't express this more precisely. I thinks it's probably
> clear... I ask as there is a piece of software I am testing on real
> genomes and their shuffled derivatives, and I want to exclude the
> possibility that the control is compromised by an inadequacy of shuffling.
>
> Cheers
> Derek
>
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--
Daniel Barker
http://bio.st-andrews.ac.uk/staff/db60.htm
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