[EMBOSS] Does emboss have a handy way for mutate a protein sequence?

Marc Logghe Marc.Logghe at DEVGEN.com
Tue Mar 7 07:59:27 UTC 2006


Can msbar do something for you ? Msbar = "Mutate sequence beyond all
recognition"

Cheers,
Marc


> -----Original Message-----
> From: emboss-bounces at emboss.open-bio.org 
> [mailto:emboss-bounces at emboss.open-bio.org] On Behalf Of Zhiqiang Ye
> Sent: Monday, March 06, 2006 10:30 PM
> To: emboss at emboss.open-bio.org
> Subject: [EMBOSS] Does emboss have a handy way for mutate a 
> protein sequence?
> 
> Dear all,
> 
>       Does emboss have a handy way for mutate a protein 
> sequence by the specified way?
> For example, I have a sequence foo.fasta
> 
> >foo
> MATSCGLLKIIQRE
> 
> It has a mutant called  'A2L'. Is there any way to do this 
> operation to output(with an option to check the foo.fasta has 
> 'A' at position
> 2):
> >foo A2L
> MLTSCGLLKIIQRE
> 
> My way:  use extractseq to extract two file: one before 
> position 2, the other after postion 2. Then creat a fasta 
> file contain 'L'.  After that,  I use union to connect these 
> 3 sequence file in to one.
> 
> Or write a perl script to do this by change a string's substring.
> 
> How If emboss could provide a 'mutate' !
> 
> Thank you :)
> 
> Best regards!
> --
> Zhiqiang Ye
> 
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