[EMBOSS] [Bioperl-l] Tool to mutate DNA sequence
Heikki Lehvaslaiho
heikki at sanbi.ac.za
Thu Feb 9 11:31:20 UTC 2006
Ryan,
Instructions in pseudo code:
take the sequence string out of the object
use a hash to store changed locations
repeat
pick a location in the string randomly
if the location is not in a hash , i.e. changed already,
change it into something else
add the changed location into the hash
if enough locations have been changed (scalar keys hash), exit loop
put the sequence string back into the seq object
-Heikki
On Thursday 09 February 2006 06:46, Ryan Golhar wrote:
> Does anyone know of tool to mutate a DNA sequence by a specified amount?
> For instance, say I have a DNA sequence 1000 bases long, and I want to
> simulate mutations to make it 75% (or 80%, etc) similar to the original.
>
>
> Ryan
>
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> Bioperl-l at lists.open-bio.org
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--
______ _/ _/_____________________________________________________
_/ _/
_/ _/ _/ Heikki Lehvaslaiho heikki at_sanbi _ac _za
_/_/_/_/_/ Associate Professor skype: heikki_lehvaslaiho
_/ _/ _/ SANBI, South African National Bioinformatics Institute
_/ _/ _/ University of Western Cape, South Africa
_/ Phone: +27 21 959 2096 FAX: +27 21 959 2512
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