[EMBOSS] RE: Silent Mutations

[simon andrews (BI)]

> -----Original Message-----
> From: Sylvie Urbé [mailto:urbe at liverpool.ac.uk]
> Sent: 22 August 2003 13:48
> To: emboss at embnet.org
> Subject: 
> 
> 
> Does EMBOSS contain an application that allows 
> introduction of new restrictionsites as silent 
> mutations in a given ORF?

If you're not sure of the name of an EMBOSS program
to perform a specific task (or even if one exists
at all), you can use the wossname program to search
for it.

In this case:

$ wossname mutation
Finds programs by keywords in their one-line documentation

SEARCH FOR 'MUTATION'
silent           Silent mutation restriction enzyme scan


Once you've found a likely program you can read its
full documentation using tfm


$ tfm silent
Displays a program's help documentation manual

                                  silent 
                                        
Function

   Silent mutation restriction enzyme scan
   
Description

   silent does a scan of a nucleic acid sequence for silent mutation
   restriction enzyme sites.
   
   silent finds positions in a sequence where a point mutation could be
   made to introduce a specified restriction enzyme recognition site
   without changing the translation.

Hope this helps

Simon.