[Dynamite] Is this working now then?

Ewan Birney birney@ebi.ac.uk
Tue, 7 Mar 2000 06:26:32 +0000 (GMT)


On Mon, 6 Mar 2000, Ian Holmes wrote:

> On Mon, 6 Mar 2000, Ewan Birney wrote:
> 
> > > > (NB I think all alignment algorithms should be global at the minute. Doing
> > > > local alignment is effectively an optimisation step, equivalent to saying
> > > > that some cells are zero throughout the matrix)
> > > 
> > > No!  I'm v.against implementing everything as global and hacking in
> > > local alignments later.  Something like that needs to work from the start.
> > 
> > I am with Guy here actually. We will need global/local switches to be
> > nicely placed in the models.
> 
> I feel like I am swimming upstream here Ewan. This is not the first time
> we've discussed global/local models, only the first time on this list...
> have you changed your mind recently?

Bugger. I am now caught agree with *both* you and Guy. I have to think 
about this a bit more.


> 
> 
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