[Biopython] comparing micro array data

[Peter]

On Tue, Mar 16, 2010 at 4:56 PM, Sean Davis <sdavis2 at mail.nih.gov> wrote:
>
> If you don't mind a couple of questions, for curiosity sake, how big is the
> genome of model organism?  And what size are the arrays, in terms of
> probes?

Also, what kind of organism? e.g. Plant, animal, bacteria? This will
make a difference for the number of papers you'll find doing this kind
of thing in the literature.

On Tue, Mar 16, 2010 at 4:49 PM, Vincent Davis  wrote:
> I actually was brought into this project by a team from an university. They
> know lots including that this is a difficult problem. They did not have any
> references as to how others have solved this problem with whatever success
> was possible. Since I know python, biopython has been my first choice to ask
> other smart people :)

For a recent example using microarrays for cross-species comparison
(aka microarray comparative genomic hybridisation) in bacteria you
might want to read Leighton's paper (and the references within - which
include work on humans):

http://www.ncbi.nlm.nih.gov/pubmed/19696881

You can probably guess why he asked if you were doing array CGH ;)

Peter