[Bioperl-l] Compliance of Bio::Seq add_SeqFeature() method
Florent Angly
florent.angly at gmail.com
Mon Mar 5 07:39:08 UTC 2012
Hi all,
I have just been burned by a problem with the Bio::Seq add_SeqFeature()
method. Bio::Seq is a class which implements Bio::SeqI, which itselt
implements Bio::FeatureHolderI, which defines an add_SeqFeature() method as:
> Usage : $feat->add_SeqFeature($subfeat);
> $feat->add_SeqFeature($subfeat,'EXPAND')
> Function: adds a SeqFeature into the subSeqFeature array.
> with no 'EXPAND' qualifer, subfeat will be tested
> as to whether it lies inside the parent, and throw
> an exception if not.
>
> If EXPAND is used, the parent''s start/end/strand will
> be adjusted so that it grows to accommodate the new
> subFeature
> Example :
> Returns : nothing
> Args : a Bio::SeqFeatureI object
In comparison, the add_SeqFeature method implemented by Bio::Seq is:
> Title : add_SeqFeature
> Usage : $seq->add_SeqFeature($feat);
> $seq->add_SeqFeature(@feat);
> Function: Adds the given feature object (or each of an array of feature
> objects to the feature array of this
> sequence. The object passed is required to implement the
> Bio::SeqFeatureI interface.
> Returns : 1 on success
> Args : A Bio::SeqFeatureI implementing object, or an array of such
> objects.
As you can see, there is a discrepancy. While the Bio::Seq method takes
an array of features, Bio::FeatureHolderI states that it should take a
single feature and the optional 'EXPAND' scalar.
It would not be very hard to modify Bio::Seq so that it complies with
Bio::FeatureHolderI. One would have to make sure that the Bio::Seq
feature takes the 'EXPAND' option and to have a deprecation message for
any call with more than one feature.
First, I am missing something here or does Bio::Seq need to comply with
Bio::FeatureHolderI?
Then, if Bio::Seq needs to be changed, I wanted to have some feedback
from other wise Bioperl-ers to see if the course of action I described
is adapted.
Best,
Florent
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