[Biojava-l] InstabilityIndex

[Andreas Prlic]

Hi Subrata,

Please don't mail me directly, but send your questions to the list.
Chances are that somebody there can help you best.

Ah Fu, do you have any thoughts on this?

Thanks,

Andreas




On Mon, Oct 8, 2012 at 12:06 PM, subrata sinha
<subratasinha2006 at yahoo.co.in> wrote:
> Dear Sir,
>
> I was testing the getInstabilityIndex() method of
> org.biojava3.aaproperties.PeptideProperties class.
>
> I am trying to find InstabilityIndex for very short segment of peptide, as
> short as two. But I am getting some surprising result in negative.Then i
> found that the method perhaps giving -ve result for ambiguous characters. So
> how to handle a situation if my protein sequence contains ambiguous
> characters
>
> Input Sequence            Instability Index
>
> GTDG                      -13.725
> VDVR                      -30.075
>
> How i analyse the above situation.
>
> Kindly help me.
>
>
> With Regards
>
> Subrata Sinha
> Assistant Professor
> Centre for Bioinformatics Studies
> Dibrugarh University