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    Thank you for your reply, Paul.<br>
    <br>
    Here is the first 18 lines of my fastq file (strangely enough it
    seems to have missed the quality coding line for the first sequence.
    However the last line of this file is a single quality code line),
    and below it are the barcodes.<br>
    <br>
    @M02850:116:000000000-ANY8B:1:1101:12375:1762 1:N:0:1<br>
CATGTAATTCAAAATCCAATAAATCAAAAATAAAAAAAATCAAAAAACAAAAAACTAATCAACATATTAAACTTTCCAAATTCATTAACCAAAAACTAATCTCACTTCTCACAAACCACATCAACTTTCTTCATTCTTCAAT<br>
    +<br>
FFFGFGGGGGGGGGHHHGHHHHHHCFHHHHHHGHHHGGGHHHHGHHGGHHHGHGGHHHHHHHGHHHHHGHHHFHHHHHHHHHHHHHHHHHFHHHFEFHHHGHHHHHHGHHHBGHHGGHGHHHHHHHHHGHHHHHHHGHHGHF<br>
    @M02850:116:000000000-ANY8B:1:1101:12375:1762 2:N:0:1<br>
CATGGTGTAAATAGTTTAAAGTATTGTTATTATGTTTATTTTTGTATGGTTTTTGGAAATTGAGAAAGAGGAGAATTTAAAGAGGATGTGTGAGAGAGATAGTTTGATTTTTTGATTGAAGAATGAAGAAAGTTGATGTGGT<br>
    +<br>
FFFGGGGGGGFGGHGHHHHHHDGGHHFHFHHHHHHGGFHHHHHCGHHHHHHHGGGGFHHHHGFHFHHFFGHHGEGHHHHHFFGGHFHHHFHHBFGFFEFHHHHHHGHHHHFHGGAGHHHHHFGHHHHGHGHHFHFHHFGHFG<br>
    @M02850:116:000000000-ANY8B:1:1101:18019:1825 1:N:0:1<br>
ATTCGAGAATCTCATATATTCTTTATCGAAACCCATACATCTTTCCGTCGAAAATCTCATATATACCTTATCCCATTCAACATTCATACGAACGCCGCTCTAGAATTTTTACTTTTCGCCATTAATCCAAATACTATTTAAT<br>
    +<br>
FFFGGGGGGGGGGHHHHHHHHHHHHHHHHHGGHGGHHHGHHHHHHHGHHGGGGGHHHHHHGHHHHHGHHHHHHHHHHHHHHHHHHHHHHHGHGGGGGGGGHHHHHHHHHHHHHHHHHGGGGGHHHHHHHHHHHHHHHHHHHH<br>
    @M02850:116:000000000-ANY8B:1:1101:18019:1825 2:N:0:1<br>
TGGAAAAAATAATAATAATTTGATTGTTAGTATTTTATAAATCGATAAATCGTAAGAAGAAAAATATAAAAATAATATTAAAGTTGTGTGCTAAAAGCAATTTTAAATAATTAAATAGTATTTGGATTAATGGCGAAAAGTA<br>
    +<br>
FFFFGGGGGGGGGHHHGHHHHHHHHHGHHHHHHHHHHHHHHHGEHAGGHHHGFHHHGHHHHHHGHHHGHGHHHHHHHHHHHGHHHHHGHHFHHHHHHHHHHHGHHHHHHHHHHHHHHHHHHHHHGGHHHHHHGGFGGGFHHH<br>
    @M02850:116:000000000-ANY8B:1:1101:16147:1845 1:N:0:1<br>
AATATATTAATATTAAAGAGTTATGGGTTGGAGTTTATATATTTTTTCGTCGAGAATTTTATATATATTTTATTTTATTTAATATTTATACGAGCGTCGTTTTAGGGTTTTTGTTTTTCGTTATTGGTTTAAGTGCTATTTG<br>
    <br>
    <br>
    FWABisF0    TATA<br>
    FWABisF1    CATA<br>
    FWABisF2    GATA<br>
    FWABisF3    GGTA<br>
    FWABisF4    CGTA<br>
    FWABisF5    AATA<br>
    FWABisF6    AGTA<br>
    FWABisR1    ATTC<br>
    FWABisR2    ACTC<br>
    FWABisR3    CATC<br>
    FWABisR4    CCTC<br>
    FWABisR5    TATC<br>
    FWABisR6    TCTC<br>
    WRKYBisF1    CAAG<br>
    WRKYBisF2    GTAG<br>
    WRKYBisF3    GGAG<br>
    WRKYBisR1    ACTG<br>
    WRKYBisR2    CATG<br>
    WRKYBisR3    TATG<br>
    <br>
    Matthew<br>
    <br>
    <div class="moz-cite-prefix">On 5/25/2016 7:32 PM, Paul Cantalupo
      wrote:<br>
    </div>
    <blockquote
cite="mid:CAJqbkv5Sk0WyK2sE1wVM89VYiErQTCgYdUwLM6jA3FuszUhEpQ@mail.gmail.com"
      type="cite">
      <div dir="ltr">
        <div class="gmail_default"
          style="font-family:verdana,sans-serif;font-size:small">Hi
          Matthew,</div>
        <div class="gmail_default"
          style="font-family:verdana,sans-serif;font-size:small"><br>
        </div>
        <div class="gmail_default"
          style="font-family:verdana,sans-serif;font-size:small">I'm not
          sure about any Bioperl modules (hopefully somebody else will
          chime in). But there are several routes for help on this
          matter.</div>
        <div class="gmail_default"
          style="font-family:verdana,sans-serif;font-size:small"><br>
        </div>
        <div class="gmail_default"
          style="font-family:verdana,sans-serif;font-size:small">
          <div class="gmail_default">1. Reply back to this message
            showing enough of your sequence file and your list of 8
            barcodes so we can provide further advice.</div>
          <div class="gmail_default">2. Post your question to <a
              moz-do-not-send="true" href="http://stackoverflow.com/"><a class="moz-txt-link-freetext" href="http://stackoverflow.com/">http://stackoverflow.com/</a></a>.
            Here though, you want to make sure follow guidelines found <a
              moz-do-not-send="true"
              href="http://stackoverflow.com/help/mcve">here</a> and <a
              moz-do-not-send="true"
              href="http://stackoverflow.com/help/how-to-ask">here</a>.<br>
          </div>
        </div>
        <div class="gmail_default"
          style="font-family:verdana,sans-serif;font-size:small">3. Post
          your question to<a moz-do-not-send="true"
            href="https://www.biostars.org/"> https://www.biostars.org/</a>.
          They probably have similar links for how to ask a good
          question like stackoverflow but I do'nt have the links for
          them.</div>
        <div class="gmail_default"
          style="font-family:verdana,sans-serif;font-size:small"><br>
        </div>
        <div class="gmail_default"
          style="font-family:verdana,sans-serif;font-size:small">Paul</div>
        <div class="gmail_default"
          style="font-family:verdana,sans-serif;font-size:small"><br>
        </div>
      </div>
      <div class="gmail_extra"><br clear="all">
        <div>
          <div class="gmail_signature">
            <div dir="ltr"><span style="font-family:times new
                roman,serif">Paul Cantalupo<br>
                University of Pittsburgh</span><br>
            </div>
          </div>
        </div>
        <br>
        <div class="gmail_quote">On Wed, May 25, 2016 at 4:08 PM,
          Matthew <span dir="ltr"><<a moz-do-not-send="true"
              href="mailto:mccormack@molbio.mgh.harvard.edu"
              target="_blank">mccormack@molbio.mgh.harvard.edu</a>></span>
          wrote:<br>
          <blockquote class="gmail_quote" style="margin:0 0 0
            .8ex;border-left:1px #ccc solid;padding-left:1ex">Are there
            any BioPerl modules that would help to split a barcoded
            fastq file ?<br>
            <br>
            I have tried FASTX-toolkit, but it does not work on
            paired-end data.<br>
            <br>
            The file I have been given is paired-end but a single file,
            and I have a list of 8 or so 4 letter barcodes.<br>
            <br>
            <br>
            Matthew<br>
            <br>
            _______________________________________________<br>
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              href="mailto:Bioperl-l@mailman.open-bio.org"
              target="_blank">Bioperl-l@mailman.open-bio.org</a><br>
            <a moz-do-not-send="true"
              href="http://mailman.open-bio.org/mailman/listinfo/bioperl-l"
              rel="noreferrer" target="_blank">http://mailman.open-bio.org/mailman/listinfo/bioperl-l</a><br>
          </blockquote>
        </div>
        <br>
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