[Bioperl-l] Re: Protein encoding by both DNA strands

[Ewan Birney]

On Sat, 24 Feb 2001, Hilmar Lapp wrote:

> Has anyone already read the article in Nature 409, 1000 (2001). I
> so far implemented that for a transcript's CDS you cannot sensibly
> mix exons from both strands (which may be narrow-minded anyway,
> because it assumes that all exons refer to the same sequence, or
> different sequences in the same direction).
> 

Yeah. Fun eh?


Delighted to say the Ensembl gene model has no difficulty with this
(though the drawing code will be interesting). I think the Bioperl gene
model and location is ok with this, but would need a convention about what
strand these beasts are on (I guess strand 0)

> This business is going to be a nightmare.
> 

At last we are not dealing with trypanosomes. Wide-spread RNA editing
would be a nightmare.


> 	Hilmar
> 
> -- 
> -----------------------------------------------------------------
> Hilmar Lapp                              email: hlapp@gmx.net
> GNF, San Diego, Ca. 92122                phone: +1 858 812 1757
> -----------------------------------------------------------------
> 

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